Afatinib

Usual solid dosage form
Tablet
Available as a liquid
No
Available as a licensed liquid formulation?
No
Liquid strengths
n/a
Liquid sugar free or not
n/a
Additional information for Healthcare Professionals+
Dissolve directly in mouth
No
Available as soluble tablets
No
Sub-lingual
No
Specially coated?
No
Available as an unlicensed special liquid formulation?
No
Licensed for administration via enteral tube
Yes
Advice on administration via enteral tube
Can be administered via NG/PEG tubes. No information available on administration via NJ/PEJ/PEGJ tubes. Stop the enteral feed before administration. Flush the feeding tube with water before and after administration of the medication. tablets can be dispersed in approximately 100 ml of non-carbonated drinking water. No other liquids should be used. The tablet should be dropped into the water without crushing it, and stirred occasionally for up to 15 min until it is broken up into very small particles. The dispersion should be administered immediately. The glass should be rinsed with approximately 100 ml of water which should also be administered. No break in feeding is required after the medication has been administered.
Available as other formulations?
No
Note
-
Film coated
Yes
Modified release
No
Enteric coated
No
Sugar coated
No
Generic drug
Afatinib
Safe or appropriate to crush
The summary of product characteristics states that tablets can be dispersed in approximately 100 ml of non-carbonated drinking water. No other liquids should be used. The tablet should be dropped into the water without crushing it, and stirred occasionally for up to 15 min until it is broken up into very small particles. The dispersion should be consumed immediately. The glass should be rinsed with approximately 100 ml of water which should also be consumed.