Desmopressin

(DDAVP®, Octim®, Desmotabs®, Desmospray®, Minirin®, Noqdirna®, Desmomelt®, Desmopressin)

Available as tablets or capsules.
Tablets
Available as soluble tablets?
No
Available as a liquid?
No
Available as something for placing under your tongue?
Yes - oral lyophilisates
Available as something for placing on your gum?
-
Available as granules?
-
Available as a patch for putting on your skin?
-
Available as an injection?
-
Available as nasal/oral spray?
-
Safe or appropriate to crush
Licensed alternative formulations available and therefore crushing is not recommended. Crushing or dispersing should always be used as a last resort but current text books and resources suggest it is likely to be safe but is not recommended for long term use.Clinicians should be aware that this is an unlicensed use of the medication.
Additional information for Healthcare Professionals+
Generic name
Desmopressin
Usual formulation brand names
DDAVP®, Octim®, Desmotabs®, Desmospray®, Minirin®, Noqdirna®, Desmomelt®
Is tablet/capsule specially coated?
No
Modified release
No
Film coated
No
Enteric coated
No
Sugar coated
No
Soluble tablet strength
-
Sublingual/buccal formulation strength
No
Granule strength
-
Transdermal patch strength
-
Injection strength
-
Nasal/oral spray Strength
-
Available as a licensed liquid or special?
No
Are specials or imports available?
Yes- oral suspension, oral solution
Liquid strengths
n/a
Is the liquid medicine sugar free?
n/a
Licensed for administration via enteral tube
No
Advice on administration via enteral tube
Change formulation to nasal route or oral lyophilisates if appropriate. Current resources suggest that it is likely to be safe to crush tablets and administer via enteral feeding tubes. Stop the enteral feed before administration. Crush tablets, add 15-30mL of water and mix well. Draw up mixture with a 50mL enteral syringe and administer via enteral feeding tube. Flush the feeding tube with water before and after administration of the medication. No break in feeding is required after the medication has been administered.
Notes
Change to alternative route where possible. There is a risk of reduced absorption if given via feeding tubes which terminate beyond the stomach.