(DDAVP®, Octim®, Desmotabs®, Desmospray®, Minirin®, Noqdirna®, Desmomelt®, Desmopressin)
Available as tablets or capsules.
Available as soluble tablets?
Available as a liquid?
Available as something for placing under your tongue?
Yes - oral lyophilisates
Available as something for placing on your gum?
Available as a patch for putting on your skin?
Available as an injection?
Available as nasal/oral spray?
Safe or appropriate to crush
Licensed alternative formulations available and therefore crushing is not recommended. Crushing or dispersing should always be used as a last resort but current text books and resources suggest it is likely to be safe but is not recommended for long term use.Clinicians should be aware that this is an unlicensed use of the medication.
Additional information for Healthcare Professionals+
Usual formulation brand names
DDAVP®, Octim®, Desmotabs®, Desmospray®, Minirin®, Noqdirna®, Desmomelt®
Is tablet/capsule specially coated?
Soluble tablet strength
Sublingual/buccal formulation strength
Transdermal patch strength
Nasal/oral spray Strength
Available as a licensed liquid or special?
Are specials or imports available?
Yes- oral suspension, oral solution
Is the liquid medicine sugar free?
Licensed for administration via enteral tube
Advice on administration via enteral tube
Change formulation to nasal route or oral lyophilisates if appropriate. Current resources suggest that it is likely to be safe to crush tablets and administer via enteral feeding tubes. Stop the enteral feed before administration. Crush tablets, add 15-30mL of water and mix well. Draw up mixture with a 50mL enteral syringe and administer via enteral feeding tube. Flush the feeding tube with water before and after administration of the medication. No break in feeding is required after the medication has been administered.
Change to alternative route where possible. There is a risk of reduced absorption if given via feeding tubes which terminate beyond the stomach.