Entacapone

(Comtess®, Entacapone)

Available as tablets or capsules.
Tablets
Available as soluble tablets?
No
Available as a liquid?
No
Available as something for placing under your tongue?
No
Available as something for placing on your gum?
-
Available as granules?
-
Available as a patch for putting on your skin?
-
Available as an injection?
-
Available as nasal/oral spray?
-
Safe or appropriate to crush
Crushing or dispersing should always be used as a last resort but current text books and resources suggest it is likely to be safe to disperse Comtess brand tablets in water. Tablets should be shaken in 10mL of water for 5 minutes before administration. Tablets should not be crushed. Clinicians should be aware that this is an unlicensed use of the medication.
Additional information for Healthcare Professionals+
Generic name
Entacapone
Usual formulation brand names
Comtess®
Is tablet/capsule specially coated?
Yes
Modified release
No
Film coated
Yes
Enteric coated
No
Sugar coated
No
Soluble tablet strength
-
Sublingual/buccal formulation strength
No
Granule strength
-
Transdermal patch strength
-
Injection strength
-
Nasal/oral spray Strength
-
Available as a licensed liquid or special?
No
Are specials or imports available?
Yes - oral solution, suspension
Liquid strengths
n/a
Is the liquid medicine sugar free?
n/a
Licensed for administration via enteral tube
No
Advice on administration via enteral tube
Current resources suggest that it is likely to be safe to administer via enteral feeding tubes, however this is an unlicensed use of the medication. Clinicians should refer to specialist resources for advice on how to administer this medication via enteral feeding tubes.
Notes
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