Isosorbide dinitrate
(Isoket®, Isosorbide dinitrate)
Available as tablets or capsules.
Tablets, Modified-Release Tablets
Available as soluble tablets?
No
Available as a liquid?
No
Available as something for placing under your tongue?
No
Available as something for placing on your gum?
No
Available as granules?
No
Available as a patch for putting on your skin?
No
Available as an injection?
Yes
Available as nasal/oral spray?
No
Safe or appropriate to crush
Consider GTN patches as an alternative. Crushing tablets should always be used as a last resort but current textbooks and resources suggest it is likely to be safe. Clinicians should be aware that this is an unlicensed use of the medication.
Additional information for Healthcare Professionals+
Generic name
Isosorbide dinitrate
Usual formulation brand names
Isoket®
Is tablet/capsule specially coated?
Yes - M/R tablets
Modified release
Yes - M/R tablets
Film coated
No
Enteric coated
No
Sugar coated
No
Soluble tablet strength
-
Sublingual/buccal formulation strength
-
Granule strength
-
Transdermal patch strength
-
Injection strength
0.05%, 0.1%, 0.5mg/ml, 1mg/ml, &10mg/10ml solution for injection; 25mg/50ml solution for infusion.
Nasal/oral spray Strength
-
Available as a licensed liquid or special?
Special
Are specials or imports available?
Special - oral solution, suspension
Liquid strengths
Check with manufacturer
Is the liquid medicine sugar free?
Check with manufacturer
Licensed for administration via enteral tube
No
Advice on administration via enteral tube
First line choice is to administer as parenteral injection if appropriate. Current resources suggest that it is likely to be safe to administer via enteral feeding tubes, however this is an unlicensed use of the medication. Clinicians should refer to specialist resources for advice on how to administer this medication via enteral feeding tubes.
Notes
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