Itraconazole

Usual solid dosage form
Capsules
Available as a liquid
Yes
Available as a licensed liquid formulation?
Yes - oral solution
Liquid strengths
10mg/mL
Liquid sugar free or not
Yes.
Additional information for Healthcare Professionals+
Dissolve directly in mouth
No
Available as soluble tablets
No
Sub-lingual
No
Specially coated?
Yes- coated beads contained inside capsules
Available as an unlicensed special liquid formulation?
Yes - oral solution, suspension
Licensed for administration via enteral tube
No
Advice on administration via enteral tube
First line choice is to administer as parenteral infusion if appropriate. Current resources suggest that it is likely to be safe to administer solution/suspension via enteral feeding tubes, however this is an unlicensed use of the medication. Clinicians should refer to specialist resources for advice on how to administer this medication via enteral feeding tubes.
Available as other formulations?
Concentrate for infusion (10mg/mL)
Note
-
Film coated
No
Modified release
No
Enteric coated
No
Sugar coated
No
Generic drug
Itraconazole
Safe or appropriate to crush
Licensed alternative formulations available and therefore crushing is not recommended. Opening capsules should always be used as a last resort but current text books and resources suggest that it is likely to be safe to open Sporanox brand capsules, but it is not recommended by the manufacturer. Clinicians should be aware that this an unlicensed use of the medication.