Usual solid dosage form
Available as a licensed liquid formulation?
Liquid sugar free or not
Additional information for Healthcare Professionals+
Dissolve directly in mouth
Available as soluble tablets
Available as an unlicensed special liquid formulation?
Licensed for administration via enteral tube
Advice on administration via enteral tube
Current resources suggest that it is likely to be safe to administer co-beneldopa dispersible tablets via enteral feeding tubes. Stop the enteral feed before administration. Place the tablet in the barrel of a 50mL enteral syringe and draw up 10-15mL of water. Shake well and wait for the tablet to dissolve before administering via enteral feeding tube. Flush the feeding tube with water before and after administration of the medication. No break in feeding is required after the medication has been administered. Levodopa is mainly absorbed in the jejunum so eneteral tubes which terminate in the jejunum may produce unpredictable drug effects.
Available as other formulations?
Conversion from modified-release capsules to dispersible tablets will require the patient to be monitored closely because the dispersible tablets have a faster onset of action and shorter duration that modified release capsules.
Co-beneldopa (levodopa/ carbidopa)
Safe or appropriate to crush
Licensed alternative formulations available and therefore crushing is not recommended. Use the dispersible tablets.