Mesalazine

Usual solid dosage form
Tablets- modified release, gastro-resistant
Available as a liquid
No
Available as a licensed liquid formulation?
No
Liquid strengths
n/a
Liquid sugar free or not
n/a
Additional information for Healthcare Professionals+
Dissolve directly in mouth
No
Available as soluble tablets
No
Sub-lingual
No
Specially coated?
Yes
Available as an unlicensed special liquid formulation?
No
Licensed for administration via enteral tube
No
Advice on administration via enteral tube
Current resources suggest that it is likely to be safe to administer Pentasa® tablets via large-bore feeding tubes. The Pentasa® tablets can be placed in the barrel of a 50mL enteral syringe and 15-30mL of water drawn up. The tablet can be shaken to aid dispersion and administered via large-bore tubes. Flush the feeding tube with water before and after administration of the medication. No break in feeding is required after the medication has been administered. Tubes may easily become blocked by this medicatio so the tube must be flushed well after each dose and only wide tubes should be used.
Available as other formulations?
rectal foam enema, retention enema, suppositories, granules, E/C tablets, M/R tablets
Note
Consider rectally administered formulations as an alternative if appropriate.
Film coated
Yes
Modified release
Yes, some
Enteric coated
Yes, some
Sugar coated
-
Generic drug
Mesalazine
Safe or appropriate to crush
For patients with swallowing difficulties consider giving the modified release granules or, according to the summary of product characteristics Pentasa Tablets can be dispersed in 50mL of cold water and drunk immediately. They must not be crushed or chewed.