Methotrexate
(Matrex® Metoject® , Methotrexate)
Available as tablets or capsules.
Tablets
Available as soluble tablets?
No
Available as a liquid?
Yes - oral solution
Available as something for placing under your tongue?
No
Available as something for placing on your gum?
No
Available as granules?
No
Available as a patch for putting on your skin?
No
Available as an injection?
Yes
Available as nasal/oral spray?
No
Safe or appropriate to crush
Tablets should not be crushed as the medication is cytotoxic. Use liquid alternative.
Additional information for Healthcare Professionals+
Generic name
Methotrexate
Usual formulation brand names
Matrex® Metoject®
Is tablet/capsule specially coated?
No
Modified release
No
Film coated
No
Enteric coated
No
Sugar coated
No
Soluble tablet strength
-
Sublingual/buccal formulation strength
-
Granule strength
-
Transdermal patch strength
-
Injection strength
1mg/40ml, 5mg/2ml, 7.5mg/0.3ml, 10mg/0.4ml, 12.5mg/0.5ml, 15mg/0.6ml, 17.5mg/0.7ml, 20mg/0.8ml, 22.5mg/0.9ml, 25mg/ml, 50mg/2ml, 500mg/20ml
Nasal/oral spray Strength
-
Available as a licensed liquid or special?
Yes
Are specials or imports available?
N/A licensed alternative available
Liquid strengths
2mg/ml
Is the liquid medicine sugar free?
Yes some- check individual manufacturer information
Licensed for administration via enteral tube
No
Advice on administration via enteral tube
Current resources suggest that it is likely to be safe to administer the liquid via enteral feeding tubes, however this is an unlicensed use of the medication. Clinicians should refer to specialist resources for advice on how to administer this medication via enteral feeding tubes.
Notes
Caution - cytotoxic.