Osimertinib
(Tagrisso, Osimertinib)
Available as tablets or capsules.
Tablets
Available as soluble tablets?
No
Available as a liquid?
No
Available as something for placing under your tongue?
No
Available as something for placing on your gum?
No
Available as granules?
No
Available as a patch for putting on your skin?
No
Available as an injection?
No
Available as nasal/oral spray?
No
Safe or appropriate to crush
If the patient is unable to swallow the tablet, the tablet may first be dispersed in 50 mL of non-carbonated water. It should be dropped in the water, without crushing, stirred until dispersed and immediately swallowed. An additional half a glass of water should be added to ensure that no residue remains and then immediately swallowed. No other liquids should be added.
Additional information for Healthcare Professionals+
Generic name
Osimertinib
Usual formulation brand names
Tagrisso
Is tablet/capsule specially coated?
Yes
Modified release
No
Film coated
Yes
Enteric coated
No
Sugar coated
No
Soluble tablet strength
-
Sublingual/buccal formulation strength
No
Granule strength
-
Transdermal patch strength
-
Injection strength
-
Nasal/oral spray Strength
-
Available as a licensed liquid or special?
No
Are specials or imports available?
No
Liquid strengths
N/A
Is the liquid medicine sugar free?
N/A
Licensed for administration via enteral tube
Yes
Advice on administration via enteral tube
If administration via nasogastric tube is required, It should be dropped in the water, without crushing, stirred until dispersed using volumes of 15 mL for the initial dispersion and 15 mL for the residue rinses. The resulting 30 mL of liquid should be administered as per the naso-gastric tube manufacturer's instructions with appropriate water flushes. The dispersion and residues should be administered within 30 minutes of the addition of the tablets to water.
Notes
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