Sodium phenylbutyrate
(Ammonaps®, Sodium phenylbutyrate)
Available as tablets or capsules.
Tablets
Available as soluble tablets?
No
Available as a liquid?
No
Available as something for placing under your tongue?
No
Available as something for placing on your gum?
No
Available as granules?
Yes
Available as a patch for putting on your skin?
No
Available as an injection?
No
Available as nasal/oral spray?
No
Safe or appropriate to crush
Licensed alternative formulations available and therefore crushing is not recommended.
Additional information for Healthcare Professionals+
Generic name
Sodium phenylbutyrate
Usual formulation brand names
Ammonaps®
Is tablet/capsule specially coated?
No
Modified release
No
Film coated
No
Enteric coated
No
Sugar coated
Granules are sugar and maize starch based
Soluble tablet strength
-
Sublingual/buccal formulation strength
-
Granule strength
483mg/g
Transdermal patch strength
-
Injection strength
-
Nasal/oral spray Strength
-
Available as a licensed liquid or special?
No
Are specials or imports available?
Yes- suspension/solution
Liquid strengths
Check with specials manufacturer
Is the liquid medicine sugar free?
Check with specials manufacturer
Licensed for administration via enteral tube
No
Advice on administration via enteral tube
Because of its slow dissolution, granules should not be administered by nasogastric or gastrostomy tubes.
Notes
contraindicated during pregnancy and breastfeeding. The granules can be directly swallowed with a drink (water, fruit juices, protein-free infant formulas) or sprinkled on to a spoonful of solid foods (mashed potatoes or apple sauce); in this case, it is important that it is taken immediately in order to preserve the taste-masking.