Sodium phenylbutyrate

(Ammonaps®, Pheburane®, Sodium phenylbutyrate)

Available as tablets or capsules.
Tablets
Available as soluble tablets?
No
Available as a liquid?
No
Available as something for placing under your tongue?
No
Available as something for placing on your gum?
-
Available as granules?
-
Available as a patch for putting on your skin?
-
Available as an injection?
-
Available as nasal/oral spray?
-
Safe or appropriate to crush
Licensed alternative formulations available and therefore crushing is not recommended.
Additional information for Healthcare Professionals+
Generic name
Sodium phenylbutyrate
Usual formulation brand names
Ammonaps®, Pheburane®
Is tablet/capsule specially coated?
No
Modified release
No
Film coated
No
Enteric coated
No
Sugar coated
Pheburane 483 mg/g granules (For each gram of sodium phenylbutyrate, 124mg sodium and 786mg sucrose) - contraindicated during pregnancy and breastfeeding
Soluble tablet strength
-
Sublingual/buccal formulation strength
No
Granule strength
-
Transdermal patch strength
-
Injection strength
-
Nasal/oral spray Strength
-
Available as a licensed liquid or special?
No
Are specials or imports available?
Yes- suspension/solution
Liquid strengths
Check with specials manufacturer
Is the liquid medicine sugar free?
Check with specials manufacturer
Licensed for administration via enteral tube
Yes, Ammonaps® granules are licensed for administration via gastrostomy or nasogastric tubes. See the SPC for further information
Advice on administration via enteral tube
The Ammonaps® granules can be administered via enteral feeding tubes. Stop the enteral feed before administration. Add the required dose of Ammonaps® granules to 10mL of water for every 5g of granules and stir to produce a milky-white suspension.. Draw up the suspension with an enteral syringe. Flush the feeding tube with water before and after administration of the medication. No break in feeding is required after the medication has been administered.
Notes
The granules should be mixed with solid foods (such as mashed potatoes or apple sauce) or liquid foods (such as water, apple juice, orange juice or protein-free infant formulas).