Topiramate
(Topamax®, Topiramate)
Available as tablets or capsules.
Tablet
Available as soluble tablets?
No
Available as a liquid?
Yes
Available as something for placing under your tongue?
No
Available as something for placing on your gum?
No
Available as granules?
Yes - Capsules containing spinkles
Available as a patch for putting on your skin?
No
Available as an injection?
No
Available as nasal/oral spray?
No
Safe or appropriate to crush
Licensed alternative formulations available and therefore crushing is not recommended.
Additional information for Healthcare Professionals+
Generic name
Topiramate
Usual formulation brand names
Topamax®
Is tablet/capsule specially coated?
Yes
Modified release
No
Film coated
Yes
Enteric coated
No
Sugar coated
No
Soluble tablet strength
-
Sublingual/buccal formulation strength
-
Granule strength
15mg, 25mg & 50mg Capsules containing sprinkles
Transdermal patch strength
-
Injection strength
-
Nasal/oral spray Strength
-
Available as a licensed liquid or special?
Licensed - oral suspension
Are specials or imports available?
Alternative strengths on Specials Tariff
Liquid strengths
10mg/ml, 20mg/ml - licensed; 25mg/5ml - Special
Is the liquid medicine sugar free?
Yes
Licensed for administration via enteral tube
No
Advice on administration via enteral tube
Current resources suggest that it is likely to be safe to administer via enteral feeding tubes, however this is an unlicensed use of the medication. Clinicians should refer to specialist resources for advice on how to administer this medication via enteral feeding tubes.
Notes
The clinical effectiveness of topiramate may be reduced if administered via tubes which terminate in the jejunum. There may be variability between brands of topiramate, so every effort should be made to maintain the patient on the same brand if the medication is being used for seizure control. Where changes in brand or formulation are unavoidable the patient must be closely monitored.