Voriconazole

(VFEND®, Voriconazole)

Available as tablets or capsules.
Tablets
Available as soluble tablets?
No
Available as a liquid?
Yes
Available as something for placing under your tongue?
No
Available as something for placing on your gum?
No
Available as granules?
No
Available as a patch for putting on your skin?
No
Available as an injection?
Yes
Available as nasal/oral spray?
No
Safe or appropriate to crush
Licensed alternative formulations available and therefore crushing is not recommended. Crushing or dispersing should always be used as a last resort but current text books and resources suggest that it is likely to be safe. Clinicians should be aware that this an unlicensed use of the medication.
Additional information for Healthcare Professionals+
Generic name
Voriconazole
Usual formulation brand names
VFEND®
Is tablet/capsule specially coated?
Yes
Modified release
No
Film coated
Yes
Enteric coated
No
Sugar coated
No
Soluble tablet strength
-
Sublingual/buccal formulation strength
-
Granule strength
-
Transdermal patch strength
-
Injection strength
200mg powder for infusion
Nasal/oral spray Strength
-
Available as a licensed liquid or special?
Licensed
Are specials or imports available?
N/A licensed alternative available
Liquid strengths
40mg/1ml powder for suspension
Is the liquid medicine sugar free?
No
Licensed for administration via enteral tube
No
Advice on administration via enteral tube
If possible the infusion should be used as first line. Current resources suggest that it is likely to be safe to administer via enteral feeding tubes, however this is an unlicensed use of the medication. Clinicians should refer to specialist resources for advice on how to administer this medication via enteral feeding tubes.
Notes
Bioavailability is reduced by high fat meals