Zidovudine

(Retrovir®, Combivir®(with lamuvidine), Zidovudine)

Available as tablets or capsules.
Capsules
Available as soluble tablets?
No
Available as a liquid?
Yes
Available as something for placing under your tongue?
No
Available as something for placing on your gum?
-
Available as granules?
-
Available as a patch for putting on your skin?
-
Available as an injection?
-
Available as nasal/oral spray?
-
Safe or appropriate to crush
Licensed alternative formulations available and therefore crushing is not recommended. SPC states Combivir tablets may be crushed and added to a small amount of semi-solid food or liquid, all of which should be consumed immediately.
Additional information for Healthcare Professionals+
Generic name
Zidovudine
Usual formulation brand names
Retrovir®, Combivir®(with lamuvidine)
Is tablet/capsule specially coated?
No
Modified release
No
Film coated
-
Enteric coated
-
Sugar coated
-
Soluble tablet strength
-
Sublingual/buccal formulation strength
No
Granule strength
-
Transdermal patch strength
-
Injection strength
-
Nasal/oral spray Strength
-
Available as a licensed liquid or special?
Yes
Are specials or imports available?
n/a
Liquid strengths
50mg/5mL
Is the liquid medicine sugar free?
Yes
Licensed for administration via enteral tube
No
Advice on administration via enteral tube
Cuurent resources suggest using the parenteral injection as first line if possible. If not possible additonal resources suggest that it is likely to be safe to administer to administer the oral solution via enteral feeding tubes. Stop the enteral feed before administration. Flush the feeding tube with water before and after administration of the medication. No break in feeding is required after the medication has been administered.
Notes
Monitor for increased side effects or loss of efficacy (if administering via enteral route).