Zonisamide
(Zonegran®, Desizon®, Zonisamide)
Available as tablets or capsules.
Capsules
Available as soluble tablets?
No
Available as a liquid?
Yes
Available as something for placing under your tongue?
No
Available as something for placing on your gum?
No
Available as granules?
No
Available as a patch for putting on your skin?
No
Available as an injection?
No
Available as nasal/oral spray?
No
Safe or appropriate to crush
N/A licensed oral liquid is available (Desizon®)
Additional information for Healthcare Professionals+
Generic name
Zonisamide
Usual formulation brand names
Zonegran®, Desizon®
Is tablet/capsule specially coated?
No
Modified release
N/A - zonisamide has a long half-life which provides once a day dosing
Film coated
No
Enteric coated
No
Sugar coated
No
Soluble tablet strength
-
Sublingual/buccal formulation strength
-
Granule strength
-
Transdermal patch strength
-
Injection strength
-
Nasal/oral spray Strength
-
Available as a licensed liquid or special?
Licensed- Oral Suspension
Are specials or imports available?
Licensed oral Liquid is available, but alternative strength on Specials Tariff
Liquid strengths
20mg/ml - licensed, 50mg/5ml - special
Is the liquid medicine sugar free?
Yes
Licensed for administration via enteral tube
Yes
Advice on administration via enteral tube
Desizon® may also be administered via a feeding tube that must be rinsed three times immediately after administration with at least 5 ml of water for each rinse. Four different sizes (CH 4.5, CH 6, CH 9 and CH 12) of PVC tubes for gastric or enteric feeding with a length of 50 cm have been tested. If this method of administration is used, the suspension should be prepared as described above for oral use immediately before administration.
Notes
Desizon® oral suspension may be swallowed directly from the oral syringe followed by a glass of water. Alternatively, the oral suspension may also be diluted in a glass of water or orange juice. Carbonated beverages such as sparkling water should not be taken with the suspension.